Endocrine Abstracts

Materials and methods: We studied 30 MO patients with OSA without Continuous Positive Airway Pressure (CPAP) treatment, before and one year after surgery. All patients underwent overnight conventional polisomnography (CE-Series Compumedics, Victoria, Australia). Sleeve gastrectomy or Roux-en-Y gastric bypass were performed according to the local protocol. To asses AS, augmentation index adjusted for heart rate (IAx@75) was obtained by applanation tonometry (Sphygmocor&#17...

Introduction: HO1 is a new adipokine with a protective role against cellular stress and hypoxia1. MO presents with high low grade inflammation (LGI)2 and high circulating levels or adipose tissue expression of HO13. The effect of bariatric surgery on HO1 and its relationship with OSA and LGI has not yet been studied.Methods: We studied 66 MO patients before and 1 year after BS. All of them presented OSA without Continuous...

Introduction: Obesity and its comorbidities, specially type 2 diabetes (T2D), are a major public health problem. The disappointing result of dietary treatment and the scarce of drugs have led to increased bariatric surgery (BS) as the most efficient therapeutic option. However, not all obese patients with T2D who undergo BS achieve diabetes remission.Objective: To develop a genetic scoring system for predicting T2D remission following BS. 2) To compare o...